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Human Islet Cells

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Human Islets for Research (HIR)® are primary human islets processed from organ donor pancreases that have been approved for research but not for clinical transplantation of either the pancreas or the isolated islets.

HIR® are obtained in a proprietary process of pancreas digestion and islet purification that result in uniformly high quality HIR® available to diabetes research investigators.

 

 

Using Prodo Labs protocols and kits, the human pancreases are delivered under controlled temperature conditions directly from the recovering hospital to Prodo Labs, with appropriate paper work confirming documented informed consent. Each cadaver organ donor must meet specific criteria including freedom from specific diseases, risks, and blood test and drug screen results before Prodo Labs will accept these pancreases for processing into human islets for research.

Before being made available, the islets are held on tissue culture for 2-3 days to ensure they are of high quality. As a number of preparations do not immediately show damage from donation and processing, Quality Control (QC) testing is routinely performed prior to release to ensure uniform quality and function of these islets.

 

 

Interested in using these HIR®?
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Which Human Islets can you order?

When a new lot becomes available, you can order different sizes of HIR®.

Your local tebu-bio office will be pleased to help you with your order, and to provide pricing for the quantity of HIR® you wish to purchase.

Specially formulated media to optimise HIR® use

Designation Cat. Nr. Description Size
PIM(R)® PIM-R001GMP Islet Recovery medium for 1st 48 hours of tissue culture. Requires PIM(ABS) & PIM(G) for activation. 500 ml
PIM(S)® PIM-S001GMP Standard islet medium for short and long term culturing. Requires PIM(ABS) & PIM(G) for activation. 500 ml
PIM(T)® PIM-T001GMP Islet transport medium for cold or ambient temperature shipping. Requires PIM(ABS) & PIM(G) for activation. 500 ml
PIM(ABS)® PIM-ABS001GMP Human AB serum supplement for PIM(R), PIM(S) & PIM(T) 25 ml
PIM(G)® PIM-G001GMP Glutamine & glutathione used to supplement PIM(R), PIM(S), & PIM(T) 5 ml

We strongly advise using Prodo Labs specially formulated media to ensure optimal use of your HIR®.


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