tebu-bio is a European company specialised in providing innovative reagents and laboratory services in Life Sciences
X

Need an answer now?

Give us a call

Leave a message, we'll get back to you





Rat and Mouse Skin Microsomes & S9

See the related products

Many drug metabolizing enzymes of the liver and other visceral organs are also expressed in the skin. The skin possesses a broad spectrum of xenobiotic metabolizing enzymes including cytochromes P450, flavin monooxygenases, esterases/amides, UDP-glucuronosyltransferases, glutathione S-transferases and sulfotransferases. Specific activities of these cutaneous enzymes are typically less than 10% of those found in the liver, yet they may play a significant role in the biotransformation of xenobiotics absorbed and/or delivered through the skin.

Characterisation provided

Microsomes

Suspension buffer: 250mM sucrose

S9 Fraction

Suspension buffer: 50mM TRIS HCl (pH 7.4 at 4°C) containing 150mM KCl and 2 mM EDTA

 


See the related products