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Small GTPase Product Guide

Finding the right product suited to your application is important - to help you in choosing, we have created the following Product Guide. Our technical specialists will also be pleased to help you with your selection.

Simply click on any of the topics below to access full information:

 


Activation Assays

G-LISA:
A revolutionary new way of doing Small G-protein Activation Assays!

G-LISA assays are simple, fast (<3 hours), require only small amounts of sample (5-25 µg cell protein), yield quantitative and accurate data and are suitable for high thoughput screens. Learn more here.

 Pull-down

RhoGAP& RhoGEF activity assays
The Ras superfamily of small GTPases serve as binary switches cycling between a GDP-bound “OFF state” and a GTP-bound “ON state”, which mediates signals downstream. In cells, the cycling between the two states is mainly controlled by two types of regulatory proteins: the activating Guanine nucleotide Exchange Factors (GEFs) and the inactivating GTPase Activating Proteins (GAPs).

 


Inhibitor & Activators

Rho Inhibitor

 

Activators

 


Purified proteins

GTPases

 

Effector fragments

 

GTPase activating protein (GAPs)

Guanine nucleotide dissociation inhibitors (GDIs)

Guanine nucleotide exchange factors (GEFs)

 


Antibodies

 

Total RhoA level measurement

Faster, easier and more robust than conventional Western blot, the RhoA ELISA kit is designed as a highly selective sandwich ELISA format for RhoA measurement in cell and tissue samples in less than 5 hours.


Phosphate quantification

Cytoskeleton Inc. has introduced the largest range of highly robust phosphate assays currently available