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My accountEasyCyp Bactosomes
See the related productsBactosomes are bacterial membranes containing the human cytochrome P450s coexpressed with human NADPH-cytochrome P450 reductase. Bactosomes can be used in conjunction with the Simcyp simulator.
For the ultimate in convenience, selected CYPs are also available in the EasyCYP format, offering standard CYP concentration, standard protein concentration, and a standard vial size throughout the range.
Setting new standards for ease-of-use
- CYP concentration: 1 nmol/ml
- Protein concentration : 10 mg/ml
- Vial size: 0.5 ml
Control Easy CYP Bactosomes are supplied at 10 mg protein per ml. Each vial contains 5 mg protein.
High or low reductase?
Bactosomes are available in High Reductase & Low reductase formats.
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High Reductase
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Low Reductase
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Characteristics
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| Higher activity | Lower activity | |
| Shorter time linearity | Longer time linearity | |
| May not reflect in vivo | Better reflects in vivo | |
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Applications
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| Reaction phenotyping | Some reaction phenotyping | |
| Metabolite profiling | High throughput inhibition screening | |
| ID minor metabolites | ||
| Some inhibition screening |
Note: ‘R’ = high reductase, ‘LR’ = low reductase, except for CYP2C9 (‘HR’ = high reductase, ‘R’= low reductase’)
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