Revivocell - Next dimension of cell culture technology
Mimicking body-like conditions in one plate

To test cell-cell interactions and mimic body-like conditions, you usually need to use organ-on-a-chip technologies. However, this technology has various disadvantages such as being difficult to use, limited throughput and requiring significant investment.
How does it work? |
BenefitsQuick and simple analysis
Visualise and monitor in real-time
Saves time
Easy to set up “Plug and Play” Block design also facilitates modification of experiments in real time.
More Productive
Perform multiple experiments simultaneously in one platform
Produce reliable data
Designed in a standard SBS plate format to work with regular CO2 incubator and readout equipment. This enables you to minimize environmental differences.
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Components
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CELLBLOKS® platform has dimensions of a SBS standard Tissue Culture well plate. It has four sperate elongated channels with location for three separate Blocks. Each channel is filled with media (3-5 ml) to allow the cell-cell communication between the Blocks |
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FILTERED AIR FLOW
Better ways to reduce contamination, media evaporation and avoid pH drifts
The CELLBLOKS® chamber comes with new design Clip-Closure "Air-Lid" feature with two side clips that make it easy to create 100% hermetic seal around the chamber.
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1. Circulatory BlocksTM provide a flat plastic surface for cells to grow with side circulatory windows on the walls allowing selective media diffusion (both inlet and outlet, simulating organs in systematic circulation e.g. liver, brain, heart, lung). |
2. Barrier BlocksTM contain a selective permeable membrane on the bottom of the Block, allowing cell to proliferative on basolateral membrane (simulating epithelial cells and tissues). |
3. Blank BlocksTM have the same flat surface as the Circulatory Blocks for cell growth but no inlet or outlet for media diffusion. Blank Blocks are used to isolate cell cultures from other compartments and are often used as controls. |
How do the molecules diffuse between the Blocks
Applications
- Study the absorption, distribution and metabolism (ADME) for drug discovery
- Liver Modelling for pre-clinical Drug induced liver injury (DILI) screening (case study below)
- First pass metabolism of drugs incorporating GI and Liver compartments
- Modelling of Skin layers
- Tissue engineering
- Stem cell interaction with cancer and immune compartments
Case Studies

