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Monitoring actin dynamism is now possible!

New and unique live cell actin probes

Visualising actin dynamics has always been a real challenge. For this reason,  Spirochrome decided to develop unique probes: the SPY555- & SPY650-FastAct(TM). These new probes based on the SPY probes technology allows to label very fast actin dynamics. These probes presents many advantages - it does not require any genetic manipulation, transfection or overexpression of  fluorescent proteins. Moreover, FastAct(TM) probes are based on bright, photostable, orange fluorophore  (SPY555-FastAct(TM)) or far red fluorophore (SPY650-FastAct(TM)) which is far superior than fluorescent proteins.


SPY555- & SPY650-FastActTM benefits


Label very fast
Actin Dynamics

Microscope Compatibility

Very Specific Non Toxic



  • Label very fast actin dynamics: unique probe to label very fast actin dynamics.

  • Super-resolution Microscopes Compatibility: it can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue.

  • Very Specific: its optimized structure allows to label F-actin in live cells with high specificity.

  • Non Toxic: its non-toxic nature allows unbiased in vivo analysis.

  • Multicolor imaging: compatible with other SPY probes.


Order your FastActTM probes now


Multicolor imaging for multiple analysis

Do you want to perform advanced analysis? FastAct(TM) probes enables multicolor imaging with other SPY probes : SPY505, SPY555, SPY595,  SPY700 or GFP and m-cherry. Thanks to SPY555- & SPY650-FastAct's amazing capabilities, studying all the cytoskeleton's features has never been so easy!