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Detect SARS-CoV-2 Neutralization Antibodies by ELISA

The new cPass™ SARS-CoV-2 Neutralization Antibody Detection Kit (a.k.a. SARS-CoV-2 Surrogate Virus Neutralization Test (sVNT) Kit) is an ideal alternative to the conventional neutralizing antibody tests, such as:

  • Virus neutralization test (VNT),
  • Pseudo-virus neutralization test (pVNT),
  • Plaque reduction neutralization test (PRNT)

With the cPass™ kit, you can measure functional neutralizing antibodies (NAbs) within an hour without requiring live biological materials or strict biosafety containment for testing (i.e. BSL3 containment).

Be among the first to order this kit!

Principle of cPass™ SARS-CoV-2 Surrogate Virus Neutralization Test (sVNT) Kit

The cPass™ Neutralization Antibody Detection kit detects circulating neutralizing antibodies against SARS-CoV-2 that block the interaction between the receptor binding domain (RBD) of the viral spike glycoprotein with the ACE2 cell surface receptor.

 Applications:

  • Vaccine and Biologics development leading to production of COVID-19 neutralizing antibodies in human or animal samples.
  • COVID-19 Epidemiology Studies: investigations of sero-prevalence, assessment of herd immunity, longevity of protective immunity, efficacy of vaccine candidates as well as tracking infection in animals.
  • Viral spike glycoprotein (RBD)/ACE2 receptor interaction studies.

Main features & benefits

  • Simple - Competitive ELISA (no live biological materials or strict biosafety containment required for testing)
  • Fast - Results in one hour
  • Scalable - 96-well plate format (12 strips of 8 wells) compatible with automation
  • Convenient - Can be done in any laboratory setting
  • Easy-to-use - Positive & negative controls included
  • Versatile - Compatible with serum, plasma and media
  • Sensitive & specific - Species & isotype independent with no cross-reactivity with flu and other viral diseases (cross-reactivity only seen with SARS-CoV-1)