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Ultra sensitive detection of pathway signalling events

Signal-Seeker kits help you to discover new signal pathway events involving dynamic protein modifications such as ubiquitination, acetylation, SUMOylation and phosphorylation.

The power of Signal-Seeker™ kits lies in their optimized reagents which enables sub-nanogram detection levels of protein modifications, and the BLASTR™ buffer system that allows you to utilize a single extract to examine different protein modification changes.

New IF Tools for Acetyl lysine detection by Cytoskeleton at tebu-bio.com

Signal-Seeker advantages

  • Unparalleled sensitivity due to optimized kit reagents
  • Discover and publish novel regulatory mechanisms
  • Confirm transfection & proteomic results with endogenous data
  • Examine protein modification crosstalk

*Offer valid for items mentioned at the link above, valid up to June 30th 2019.
Your order must mention offer 027C32019 for 20% discount to be applied to the elligible Signal Seeker kits on your order.

Non cumulative with any other discounts, special offers or price agreements.


Interested in learning more about these tools?

Utilization of newly developed mouse monoclonal anti-acetyl lysine antibodies in western blot and immunoprecipitation applications
by Cytoskeleton Inc.

"We have recently developed two mouse monoclonal anti-acetyl lysine (Ac-K) antibodies that have demonstrated excellent ability in enriching acetylated proteins from cell and tissue extracts. The antibodies were raised against a proprietary mixture of acetylated proteins designed to optimize acetyl lysine recognition..."

Download the White Paper

Brochures - read more about all the Signal-Seeker kits

Signal Seeker kit for mono- and poly-ubiquitin UBD detection

Signal Seeker kit for Acetyl-Lysine detection and visualization

Signal Seeker kit for endogenous SUMO 2/3 detection



Video - Understand how Signal-Seeker detection kits work

Watch the peer-reviewed methodology video on JoVE:

"Utilizing a Comprehensive Immunoprecipitation Enrichment System to Identify an Endogenous Post-translational Modification Profile for Target Proteins"

Investigating multiple, endogenous post-translational modifications for a target protein can be extremely challenging. Techniques described here utilize an optimized lysis buffer and filter system developed with specific PTM-targeting, affinity matrices to detect the acetylation, ubiquitination, SUMOylation 2/3, and tyrosine phosphorylation modifications for a target protein using a single, streamlined system.