Discovery Tools

May 2015

News Highlight

mTOR revisited

The PI3K/Akt/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. It is directly related to cellular quiescence, proliferation, cancer, and longevity.

Discoveries made over the last decade show that the mTOR pathway is activated during various cellular processes and is deregulated in human diseases such as cancer and type 2 diabetes.


Group purchase model for oligonucleotides in Europe

Any researcher who has purchased a complex custom oligonucleotide with chemically-modified bases has probably noticed that prices drop dramatically with increased production scale, and that some companies are reluctant to promise a final yield and prefer, rather, to issue quotes for initial starting scales.

But what if researchers could get together and order a bulk purchase of commonly used oligos and benefit from the relatively low costs of bulk production?


Spring offer: 10% off Small GTPase Activation Kits

Are you looking to measure the activation of small G proteins such as Rho, Rac, Cdc42, Ras, Arf, or Ral?
Are you going to apply the classical pull-down method? Or the G-LISA technology, which gives you quantitative data?

Buy a Rockland Inc. antibody and get WB-grade non-fat milk for free

Access leading edge research tools for basic, applied and clinical research in functional genomics, gene therapy and drug discovery markets. Every lot is quality-control tested to a rigorous standard and application-tested for consistent performance.

Discover the broad selection of antibodies validated for many applications... make your choice!

Current News

User experience of SiR-Actin and SiR-Tubulin Live Cell Imaging

Recently, we launched new Live Cell Imaging tools: SiR-Actin and SiR-Tubulin, produced by Spirochrome. These stains allow you to stain actin and tubulin in living cells without the need to transfect cells.

Our specialist Ali invites you to take a look at the brilliant results users of the stains have obtained.

Read more

Focus on one of our posters presented during the AACR2015

Research performed by David García-Molleví and his team at ICO (Barcelona, Spain), in cooperation with tebu-bio laboratories, was presented at the AACR congress in Philadelphia by Nadia Normand, our R&D Manager at tebu-bio labs.

The poster describes how cytokine profiling of drug-disrupted tumour cell / fibroblast crosstalk provides insights to understand the protective role of the stroma. 

Read more

Alvetex on the International Space Station!

Alvetex Scaffold products allow researchers to overcome the limitations of growing cells on flat surfaces by creating a unique three dimensional (3D) surface that allows cells to form tissue-like structures in an in vitro setting. A team from Massachusetts General Hospital investigating bone loss during bed rest and diseases such as osteoporosis, has incorporated Alvetex Scaffold in experiments 150 miles above the surface of the Earth after the equipment is delivered to the ISS by the SpaceX Dragon capsule.. Read more...

Technical Corner

Put the odds in your favour for your STED microsopy images

High quality research antibodies, together with the use of the next generation fluorochrome conjugates, offer superior absorption and thus, high fluorescence quantum yield and superior brightness & contrast. This post displays images obtained in collaboration with Rockland Immunochemicals and Leica Microsystems. Read more...

Which Antibodies for Epigenetics?

Epigenetics research focuses primarily on histones and other proteins that control the regulation of gene expression, transcription, and protein-protein interaction. Epigenetic processes are implicated in an array of human pathophysiological conditions that include cancer, obesity, diabetes, drug addiction and post-traumatic stress disorder. 

Antibodies have been extensively used for research in Epigenetics, but not all antibodies are the same. When you choose your antibody for this area of research, make sure to follow these tips… Read more

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