Acting and reacting in Life Sciences and Biotechnologies

Acting and reacting in life sciences and biotechnologies

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JANUARY 12, 2018

Very best wishes for 2018!

We look forward to continuing to share breaking news and developments in Life Sciences with you throughout the New Year.
Stay up to date on the latest technologies and products!

Here's a selection of recent information & events...

Four new validated 3D Tissue models for more accurate in vivo-like data

In the field of Drug Development, 3D cell culture models such as spheroids or organoids currently appear as one of the best solutions to obtain accurate and physiological in vitro data, closest to what occurs in the human body. These models are the perfect intermediary between "less realistic" classical in vitro static screening well plates, and animal models which, although more relevant, are much more complicated to... [ Read more ]

Immunotherapy research: Easily build your own reporter cell line

Immunotherapy is one of the central research fields for various disease treatments and also certain cancers. A major regulator of immune homoeostasis and preventing autoimmunity, but potentially dysregulated in various cancers, Immune Checkpoint targeting has already led to promising treatment molecules (Nivolumab, Pembrolizumab…). To face the challenges of Immune system complexity and the tumour microenvironment, BPS Biosciences have developed several reporter cellular lines to complement Biochemical...  [ Read more ]

These new CF-1 Mouse Embryonic Fibroblast (MEF) feeder cells are Mitomycin-C treated, ideal for your feeder-dependent Embryonic Stem cells (ES) and induced Pluripotent Stem (iPS) cell culture.

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SiR-DNA is currently one of the best options to label DNA. Easy-to-use, non-toxic, highly specific, it can be used on various kinds of fixed or living cells. Also available: SiR-Actin, SiR-tubulin, SiR-lysosome...

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Rockland Inc are well known for their high quality, validated antibodies. Order a primary and secondary antibody to get your project going in 2018, and receive their latest t-shirt in your parcel!

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How can you improve your reporter gene assays?

Gene reporter assays are widely used in research and Drug Discovery . The development of such cell lines is often time-consuming and costly, sometimes upwards of 5-20k € per cell line. And once these cell lines are finally validated, why jeopardize your results with cheap & low-end detection kits, which might impact the reproducibility of your experiments.  BPS Bioscience has developed two reliable and extremely powerful luciferase detection kits: the ONE-Step™ Luciferase Assay System and the Dual... [ Read more ]

How can you improve your reporter gene assays

HeLa cells: Origin of this important cell line in life science research

If you work in Biology, you've most certainly heard of HeLa cells, as they have been around for over 60 years and are some of the most extensively used cell lines in Biomedical research. But where did these cell lines come from? Well, in 1951, Henrietta Lacks came into John Hopkins Hospital in Baltimore...  [ Read more ]

HeLa Cells - the first cell line

Bioactive neuronal lipid mediators: a focus on Synaptamide

Focus Biomolecules produces a broad range of bioactive lipid mediators as well as many small molecule inhibitors of numerous lipid metabolic pathways for use as cellular probes. Pathways include Anandamide, Lipo-amino acid, Prostaglandin, Leukotriene, Sphingolipid, Fatty Acid, Cholesterol and more. In this post, let's take a look at Synaptamide, an anandamide-like mediator biosynthesized from docosahexaenoic acid (DHA) in the brain... [ Read more ]

Bioactive neuronal lipid mediators: a focus on Synaptamide

GPR17 and Remyelination: activators and antagonists

The absence of mature oligodendrocytes for the repair of demyelination lesions is a critical factor in the pathology of Multiple Sclerosis (MS), and other debilitating CNS disorders of myelination. As such, regulating the maturation of oligodendrocytes and the resulting myelin production is an interesting target for potential new therapeutics. GPR17 is an orphan G-protein-coupled receptor (GPCR) that is abundant in the CNS, and has been shown to play a key role in regulating oligodendrocyte differentiation and maturation. Unfortunately, little has been known about the exact mechanism through which... [ Read more ]

Bioactive neuronal lipid mediators: a focus on Synaptamide
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