Acting and reacting in Life Sciences and Biotechnologies

Acting and reacting in life sciences and biotechnologies

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NOVEMBER 10, 2017

Acting and reacting in Life Sciences and Biotechnologies

What is "being bio-reactive"? We define it as opening new doors, exploring new areas, staying informed aboutbreaking news & developments in Life Sciences and the fast evolving world of biology.

Here's a selection of information & events from our blog this week...

How do you choose the best ELISA test for your project ?

09/11/2017 BY ISABELLE NOBIRON PhD

There are many, many ELISA tests out there to choose from, and making the best selection can sometimes be a bit daunting. In this post, let's take a look at the key points to keep in mind. One of the first thing to consider when selecting your ELISA test is of course to make sure it is tested for your species of interest :=) Apart from the standard human, mouse and rat ELISA, if you're working on canine, porcine, bovine [ Read more ]

How do you choose the best ELISA test for your project?

How is Ubiquitin implicated in cell signalling and other biological processes?

31/10/2017 BY XAVIER FAUSSADIER

The enzymatic process of ubiquitination is induced by a variety of stimuli and upstream cell signalling events. With similarities to phosphorylation, ubiquitination is emerging as a signal involved in the regulation of many biological processes. Conventional methods to detect and purify polyubiquitinated proteins often involve primary antibodies targeting ubiquitin or ubiquitin binding associated domains (UBAs). Both generally show low affinity; .. [ Read more ]

How is Ubiquitin implicated in cell signalling and other biological processes?

IDO/TDO enzymatic pathway as an additional target for Cancer Drug Discovery

30/10/2017 BY FREDERIC SAMAZAN

As a regulator of the immune system, Immune checkpoints appear to be privileged targets In Drug Discovery and Immunotherapy research. In addition to already developed Immune Checkpoint Reporter cell lines (as introduced in my previous post ), BPS Bioscience also provide tools to study the enzymatic pathway, such as the tryptophan catabolism pathway controlled by IDO1: The IDO / TDO pathway..... [ Read more ]

IDO/TDO enzymatic pathway as an additional target for Cancer Drug Discovery

Nucleosomes with native structure Next gen. tool box in epigenetic cell signalling

26/10/2017 BY XAVIER FAUSSADIER

There is a growing interest in manipulating chromatin dynamics for applications in cell signalling, drug discovery and chromatin research. Progress in this area requires the identification of design rules for the chromatin system. EpiCypher has pioneered the manufacture of nucleosomes for next generation epigenetic research and drug discovery, producing the highest quality nucleosomes available.... [ Read more ]