Tropical and vector-borne diseases account for more than 17% of all infectious diseases, causing more than 1 million deaths annually. Recognizing infected patients early in their clinical course is critical to researchers working in developing tools to prevent outbreaks. Meridian offer a range of antigens and antibodies suitable for the development of sensitive and specific immunoassays that detect tropical and vector-borne diseases. Their antibody pairs have already been validated in various immunoassays. You won’t waste time finding the right match, it has already been validated for you.
In the first part of this post, I’d like to introduce a selection of ready-to-use antibody pairs available for the main tropical and vector-borne diseases such as Chikungunya, Dengue, Ebola, Leishmania, Malaria, Yellow fever and Zika to name but a few. I’ll focus in the second part on Flavivirus immunoassay development with troubleshooting and usage tips coming from Meridian scientists to help overcoming high epitope cross-reactivity, a common issue in this specific virus family.