Nipah Virus Infection (NiV) is an emerging infectious disease of public health importance in the South-East Asia Region (source: World Health Organization). Along with Hendra virus (HeV), NiV is part of a new genus designated Henipavirus. Fruit bats have been identified as the natural reservoirs. Nevertheless, pigs, horses, goats, sheep, cats and dogs can also be infected and transmit the virus.
Symptoms of NiV infection are similar to influenza and in some cases can lead to encephalitis. The case fatality rate is high (40-70%) and there is no specific treatment. While able to bind with cellular EphrinB2, NiV G Protein (NiV-G) exhibits the antigenic epitopes and conformation necessary for specific antigen–antibody recognition. For this reason, Meridian Life Science have recently developed new Nipah virus glycoprotein (NiV-G) products suitable for the R&D projects of NiV using ELISA tests.