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tebu-bio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
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    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
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Gene Expression - Molecular Biology

Whole-genome Pol II transcription profiling by NET-Seq

12/04/2016 by Philippe Fixe, PhD No Comments
Genomics tebu-bio

Accurate monitoring of genome transcription activities is of crucial interest for deciphering gene expression and for a better understanding of RNA biology. Over the past years, various experimental methods for RNA Pol II mapping density across the whole genome have been designed. Here, I’d like to offer a brief introduction to the human Native Elongating Transcript-Sequencing (NET-Seq) method.

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Gene Expression - Molecular Biology

New: CleanTag Ligation Kit for Small RNA Library Prep

07/04/2015 by Mark Livingstone 2 Comments

As detailed in a previous post, chemically-modifying oligonucleotide adapters is an effective means to prevent adapter dimer formation during small RNA library prep. Just as primer dimers form when very little template DNA is used for PCR, adapter dimers can form with low starting concentrations of RNA. The CleanTag™ Ligation Kit for Small RNA Library Prep is a complete kit which is compatible with Illumina® technology that makes use of such modified adapters in optimized buffer conditions. The kit includes CleanTag™ chemically modified adapters that greatly reduce adapter dimer formation and is optimized for total RNA input from 1-1000 ng.

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Gene Expression - Molecular Biology, Supplying Discovery Tools

A look inside the new Otogenetics NGS library prep kits

18/03/2015 by Mark Livingstone No Comments

More than a month ago we wrote a post about the new DNASeq library prep kits from Otogenetics, a U.S. based sequencing service provider who created their own kits to reduce costs. Now, we’ve had a chance to see what the kits and their contents look like…

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Supplying Discovery Tools

High quality, low cost DNASeq kits and gene enrichment panels

12/01/2015 by Mark Livingstone No Comments

Otogenetics' kits at tebu-bioOtogenetics Corporation, a DNASeq and RNASeq next generation sequencing service provider has processed over 11,000 samples and is now producing their own DNASeq kits. In order to reduce costs and improve results, Otogenetics developed and validated kits in-house and has now made these high quality, low cost kits available to other researchers.

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