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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Supplying Discovery Tools

How to make efficient Lipid Nanoparticles for RNA delivery

27/06/2022 by Frédéric Samazan No Comments

Even if RNA-based therapeutics have been under development for over 30 years, it was the COVID-19 pandemic that brought them into the limelight, with the rapid development of mRNA-based vaccines against the SARS-Cov2 virus by Moderna and BioNTech/Pfizer. And lipid Nanoparticles (LNPs), used to efficiently deliver mRNA, are key players of this technology.

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Supplying Discovery Tools

How to make the challenge of mRNA delivery easy

12/11/2021 by Dimitri Szymczak, PhD No Comments

Many researchers are facing the challenges of mRNA delivery, through the body into the cytoplasm of cells. In this post, we invite you to discover some useful and efficient solutions to improve and control all the steps of your mRNA delivery project.

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Supplying Discovery Tools

High efficiency transfection reagents for nucleic acid delivery 

22/10/2020 by Xiyu Qian No Comments

Every type of cell has different membrane properties, meaning that transfection of your specific nucleic acid can become challenging.

To overcome transfection limitations, RJH Biosciences have developed a new range of transfection reagents to transfect mammalian cells with specific nucleic acids.

Access to this new technology now through tebu-bio in Europe!  

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Drug Discovery

Hit-and-run cell-based therapy research with Trilink mRNA

19/10/2017 by Dimitri Szymczak, PhD 2 Comments
T cells response against cancer cell

This summer, Moffett et al. published in Nature Communications (Nature Communications – doi:10.1038/s41467-017-00505-8) a new approach for cancer therapeutic research and development based on mRNA delivery. They called it ‘Hit-and-run programming’ because of the simplicity of the method. Interestingly, the optimization of the delivery was performed with eGFP mRNA.  This post describes how TriLink’s mRNAs contribute to the simple and efficient delivery of mRNA into cells.

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