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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
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Cell Biology and Signalling

3 new mitochondrial research reagents

27/10/2016 by Philippe Fixe, PhD 1 Comment
Mitochondria and mitochondrial research

Research tools aimed at exploring mitochondria are becoming more and more popular and cover multiple experimental applications. They go from primary antibodies validated for immuno-assays (see “10 Mitochondrial marker antibodies“) to fluorescent probes for mitochondria-related events monitor in living-cells (e.g. MitoPeDPP for live cell imaging, mitophagy or singlet Oxygen (1O2) detection…). Here I’d like to introduce 3 new molecules developed by Focus Biomolecules to further decipher mitochondrial biology.

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News

How to monitor mitophagy in mammalian cells

06/09/2016 by Philippe Fixe, PhD No Comments
Schematic representation of a mitochondria. Source Abnova Mitochondrial research tools by tebu-bio

Mitochondria keep cells “healthy” in their environment. In this post, we’ll take a look at a new fluorescent assay for the monitoring of mitophagy, a process aimed at clearing damaged or superfluous mitochondria by autophagy, in mammalian cells.

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Cell Biology and Signalling

MitoPeDPP: a new mitochondrial fluorescent probe for live cell imaging

25/08/2016 by Philippe Fixe, PhD No Comments
MitoPeDPP experimental results for mitochondrial research and ROS detection

Dojindo just completed its offer in the field of mitochondrial research with the release of a unique fluorescent dye for live cell imaging. This post introduces this new MitoPeDPP mitochondrial probe.

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Cell Biology and Signalling

How to detect Singlet Oxygen by live cell imaging?

27/06/2016 by Philippe Fixe, PhD No Comments
HeLa cells in fluorescent microscopy

Singlet Oxygen (1O2) fluorescent detection in living cells was limited by the lack of availability of cell membrane permeable dyes. The silicon-based far-red fluorescent probe (Si-DMA) has been especially designed to monitor singlet oxygen in real-time and in living cells. Si-DMA is now commercially available for ROS studies by live-cell imaging.

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