• Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
  • Facebook
  • LinkedIn
  • Twitter
  • Vimeo
Home
Research areas
    ADME-Tox
    Biomarkers
    Cell Biology and Signalling
    Cell Sourcing - Cell Culture Technologies
    Drug Discovery
    Gene Expression - Molecular Biology
    Stem Cells
    Supplying Discovery Tools
Contact us
Meet the authors
Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Supplying Discovery Tools

Cardiovascular disorders: Proteomics tool for disease signature identification

02/07/2018 by Isabelle Nobiron, PhD No Comments

Cardiovascular disease (CVD) comprehensively describes a range of pathologies of the heart and/or blood vessels. These disorders differ markedly in time-scale of development, and relative contributory effects of genes and environment. Largely due to this breadth, and their causes and effects, the range of investigation, assessment, and treatment strategies available is large. The diversity of the diseases, disease processes, and genetic differences between individuals could obscure disease associations in terms of the proteomic signatures of each disorder. Thus, a panel of independent disease-related proteins considered together should be less prone to this noise and help provide much more robust analysis and indication of disease. The publication featured below and the reagents (multi-plex immunoassays or single target ELISA and antibodies) mentioned in this post may contribute in helping you to identify such diseases signature.

Continue reading
Biomarkers

5 popular RayBio® ELISA kits for studying inflammation

23/11/2016 by Philippe Fixe, PhD No Comments
raybio-elisa-kit-by-raybiotech-and-tebu-bio

With more than 170,000 publications in 2016, inflammation remains a “hot” topic in today’s Life Science research (source: Google Scholar). Interestingly, the ELISA test is still one of the most popular tools for the accurate quantification of human cytokines involved in this biological process. Here, we review the 5 protein targets most studied by our clients, together with their favourite ELISA kits by RayBiotech in the field of inflammation.

Continue reading
Biomarkers

A new fast and sensitive PGE2 Immunoassay kit

30/10/2015 by Ana Arraztio No Comments
Tips from being bio-reactive
Typical Standard Curves of Our New PGE2 EIA Kit (Cat. number 183K051-H1).

Typical Standard Curves of Our New PGE2 EIA Kit (Cat. number 183K051-H1).

PGE2 is a potent lipid mediator involved in maintaining homeostasis but also in the promotion of acute inflammation or immune suppression in chronic inflammation and cancer. Recently, researchers have shown that the activation of the NLRP3 inflammasome in human primary monocyte-derived macrophages is inhibited by PGE2 (1) confirming the role of this lipid is an effective autocrine and paracrine inflammatory modulator maintaining homeostasis during the resolution phase of inflammation.

This paper also proove the importance of having access to simple but robust PGE2 quatitative assays.

Which Prostaglandin E2 (PGE2) Immunoassay kit to choose?

The Prostaglandin E2 (PGE2) Immunoassay kit is designed to quantitatively measure PGE2 present in serum, plasma, urine, saliva, cells, tissue, and tissue culture media samples. This
EIA kit allows for the widest variations in sample size, sensitivity and assay timing of any PGE2 kit:

  • Super Fast Kinetics – Same Assay Range at 2 or 16 hours
  • Incredible Sensitivity – < 2 pg/mL
  • Superior Cross Reactivity to Other Eicosanoids
  • Super Low Sample Volume Requirements
  • Choice of Incubation Time, Sensitivity, and Sample Volume in a Single Kit

Want to test this kit allowing you to accomplish any PGE2 measurement you may have, do not hesitate to contact us!

References

1.- Sokolowska, M. et al. (2015). The Journal of Immunology, vol. 194 no. 11 5472-5487. doi: 10.4049/​jimmunol.1401343.

News

Cytokine signature in airway inflammation with arrays

22/07/2015 by Ana Arraztio No Comments
Cytokine Quantibody Arrays from Raybiotech and tebu-bio laboratories

Chronic Mucosal Inflammation is the hallmark of common airway diseases (ex.  Allergic Rhinitis and asthma). Lipoxin B4(LXB4) is an endogenous mucosal protective mediator decreasing such diseases. LXB4 mechanisms of action remain poorly understood.

Cytokine Quantibody Arrays from Raybiotech and tebu-bio laboratories

Cytokine Quantibody Arrays from Raybiotech and tebu-bio laboratories.

In a recent paper in Mucosal Immunology (Karra, L. et al. (2015) 8; DOI:10.1038/mi.2014.116), Allergic Rhinitis  and asthma murine models have been described to better investigate the role of LXB4 in Mucosal Inflammation. The authors conclude that, in the upper airway, LXB4 significantly decreases nasal mucosal leukocytes and degranulation of Mast Cells (MCs) and Eosinophils. They also show that, in the lower airway, LXB4 significantly decreased airway inflammation, mucus metaplasia, and hyper-responsiveness.

Continue reading
Page 1 of 41234»

Most popular posts

  • HeLa cells: Origin of this important cell line in life science research
  • From RUO to IVD - the acronym guide to reagents' intended use
  • How to choose the perfect buffer to get a pure, stabilised, functional protein
My Tweets

Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use.
To find out more, including how to control cookies, see here: Cookie Policy

Copyright © 2018 - tebu-bio - visit our main website at tebu-bio.com

 

Loading Comments...