Acting and reacting in life science biotechnologies
JAK/STAT Pathway – Courtesy of RayBiotech
The JAK/STAT pathway is an important signalling process for numerous cytokines and growth factors.
Its activation is essential to many processes such as hematopoiesis, immune development, growth, adipogenesis, mammary gland development… [Read more…]
StemBeads® FGF2 is a revolutionary growth factor supplement that offers a more efficient way to grow FGF2 dependent stem cell cultures.
This supplement delivers a steady release of growth factor into your media of choice creating a more stable environment allowing for:
I hear you thinking “Well, that’s just more marketing promises… “. Well, it isn’t, it’s real life!
Cartilage is a flexible connective tissue which can rapidly grow and which is specialized to absorb and resist compression. The perichondrium, a vascularized layer, surrounds the tissue which does not contain any blood vessels of its own. Therefore nutrients and waste material have to be able to diffuse through the cartilage tissue. A thin layer of smooth hyaline cartilage (the so called articular cartilage) covering the joint surfaces of the bone, does not have any perichondrium though. Articular cartilage is protected by synovial fluid, a nutritive and lubricating medium. [Read more…]
Angiogenesis is the growth process of new blood vessels from pre-existing one’s. It’s a normal physiological process, observed during embryonic development. But it’s also a pathological process, essentially in the growth of malignant tumors and metastasis development.
Apoptosis is the process of programmed cell death. Upon induction of apoptotic processes, cell undergo characteristic morphological changes (blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation) and finally die.
Apoptosis has to be clearly separated from necrotic processes, which occur due to cellular injury thus being a kind of traumatic cell death. Apoptosis on the other side is a process which is necessary during the life cycle of organisms.
In a human adult, 50 – 70 billion cells die per day due to apoptosis.
Defective apoptotic processes have been linked to a number of diseases such as cancer (insufficient apoptosis) and atrophy (excessive apoptosis).
Hematology is the study of blood, blood-forming organs and blood diseases. The formation of blood cells is referred to as hematopoiesis. All cellular components of the blood are derived from hematopoietic stem cells.
Neurobiology is the study of cells of the nervous system and their organization into functional circuits that process information and mediate behavior.
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Numerous cytokines are present within inflammatory sites.
Angiogenesis is the growth process of new blood vessels from pre-existing one’s. It’s a normal physiological process, observed during embryonic development. But it’s also a pathological process, essentially in the growth of malignant tumors and metastasis development.
In my previous post, we focused on 6 cytokine growth factors for cell culture. This time, we will try to find the best factor for each main cell type.