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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Drug Discovery

cAMP signals visualized in live human pancreatic primary cells

21/07/2017 by Philippe Fixe, PhD No Comments
Montana Molecular cAMP green fluorescent sensor shows an increase of cAMP in human islets by Almaça et al. Cell 2016 DOI: http://dx.doi.org/10.1016/j.celrep.2016.11.072

In a recent publication, researchers from the University of Miami Miller School of Medicine (USA) describe that Serotonin released by human beta cell inhibits glucagon secretion by alpha cells. They demonstrated that this paracrine loop was mediated via the cAMP pathway. To do so, they captured in live human pancreatic islet cells cAMP signals using a specific fluorescent biosensor.

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Cell Biology and Signalling

3 fluorescent probes that will count in 2017

02/12/2016 by Philippe Fixe, PhD No Comments
acidifluor-orange-multicolor-fluorescence-in-hela-cells

The detection of molecular events in living cells is booming. In this post, we look at 3 fluorescent probes that will undoubtedly count in the live-cell imaging landscape in 2017.

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Cell Biology and Signalling

MitoPeDPP: a new mitochondrial fluorescent probe for live cell imaging

25/08/2016 by Philippe Fixe, PhD No Comments
MitoPeDPP experimental results for mitochondrial research and ROS detection

Dojindo just completed its offer in the field of mitochondrial research with the release of a unique fluorescent dye for live cell imaging. This post introduces this new MitoPeDPP mitochondrial probe.

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Supplying Discovery Tools

DyLight™ will be your routine fluorescent dye

01/09/2015 by Philippe Fixe, PhD 2 Comments
GST Antibody conjugated DyLight dye 488 (IF)

Rockland Immunochemicals have developed a suite of fluorescent dyes (DyLight™) with unique fluorescence intensity and photostability. Here, we take a look at how DyLight™ dyes have all the characteristics and potential to become your daily fluorescent dye conjugates.

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