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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
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    • ADME-Tox
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ADME-Tox, Headlines

Human Liver Lysosomes for in vitro catabolism testing

05/10/2018 by Jean-François Têtu, PhD 2 Comments

In this post, I’d like to introduce the Human liver Lysosomes developed by Sekisui-Xenotech, which have opened up a new era in catabolism models. Read on to learn more, and also to download a case study demonstrating the use of lysosomes for catabolism of human IgG.

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New Human Liver Lysosomes: “Our experiments went fantastically well!”

21/11/2016 by Jean-François Têtu, PhD No Comments

Hearing about results from other researchers is always interesting – we’d like to share a testimonial from our first customer using Human Liver Lysosomes. You can get an idea of how these performed in their experiments.

“Our experiments went fantastically well – we see some potential in the material as a tool to generate metabolites of interest in higher yields than the typical systems. See attached a snapshot of one experiment where we incubated a X compound in development with Hepatocytes, Microsomes and the Lysosomes you provided us with. With Lysosomes we were able to generate a metabolite (M6) with significantly higher yields and this is great because it may be a useful tool to allow full characterization of metabolites”

lysosomes-testimonials

Learn more about Human Liver Lysosomes here: Opening a new era in catabolism models

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