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You are here: Home / Archives for BPS Bioscience

New TIGIT:CD155 cell-based assay to restore immune response

23/05/2017 By Dimitri Szymczak, PhD Leave a Comment

immune inhibition and activation

TIGIT:CD155/CD112 immune inhibition (in green)

We previously addressed the PD-1:PD-L1/PD-L2 immune inhibition and the corresponding cell-based tools to screen immuno-oncology agents for restoring antitumor immune response. Unfortunately cancer cells have other ways to escape and survive. Let’s look together at another immune inhibition pathway, namely the TIGIT:CD155/CD112.

 

[Read more…]

Filed Under: Cell Biology and Signalling Tagged With: BPS Bioscience, Immuno-oncology, neutralizing antibody, TIGIT

Proteins with the High Purity (HiP™) label make the difference

07/03/2017 By Dimitri Szymczak, PhD Leave a Comment

The HiP™ (High Purity) distinction by BPS Bioscience starts, of course (as the name says), with a high purity level. But that’s not enough. Such pure proteins may aggregate, which is not compatible with binding assays. Thus, the HiP™ label also demands a low level of aggregation, or even none at all. [Read more…]

Filed Under: Supplying Discovery Tools Tagged With: Binding assay, BPS Bioscience, Cancer immunotherapy

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