On your journey to Biomarker profiling, you will reach the point where you need to quantify the proteins of interest identified along the way (eg. validation of semi-quantitative array results; biomarker discovery with an initial hunch on which pathway is involved).

At this stage, you will have narrowed down the number of targets you want to look at. However, the use of ELISAs is likely to be still too costly, too time consuming, and may require too much sample volume.

Breaking news for cancer researchers! We are pleased to have recently added innovative cancer Arrays to our product offer.  You might tell me that there are a lot of new cancer arrays every year and it’s not really necessary to write a post about it… but read on and I’m sure you’ll share my enthusiasm!

Insulin and Glucagon are involved in glucose homeostasis in addition to other factors secreted by the adipose tissue (adipokines). Insulin and Glucagon are produced by the endocrine pancreas. While Glucagon is released by alpha-cells of the islets of Langerhans to raise glycemia when blood glucose levels fall too low, Insulin has the opposite effect. Insulin is produced by beta-cells of the islets of Langerhans. It allows glucose to be taken up from the bloodstream when blood glucose levels are high and to be used by insulin-dependent tissues (liver, skeletal muscles, fat tissue…).

Let’s take a look at a selection of immuno-assays and primary cells for analysing these two hormones and the recentlly launched primary Human Islet cells.