Following up on my series of posts based on Dr Chris Bohl’s work at Sekisui Xenotech, in this post I invite you to take a look at the work he has published, together with Dr Christopher Seib, Maciej Czerwinski, Zell Woodworth and David Buckley, Ph.D., illustrating the characterization of isolated human liver lysosomes, and validating them as test systems for in vitro assessment of catabolic stability of biologics drugs entering the cell by the endosomal–lysosomal pathway.
New Human Liver Lysosomes for in vitro catabolism testing
In this post, I’d like to introduce the new Human liver Lysosomes developed by Sekisui-Xenotech that are indeed opening a new era in catabolism models.