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    ADME-Tox
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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Cell Sourcing - Cell Culture Technologies

Recent developments in 3D cell culture hydrogel

02/09/2019 by Philippe Fixe, PhD No Comments
VitroGel 3D cell culture

Due to their ability to simulate the characteristics of most soft tissues and natural scaffolds, hydrogels are now an attractive material for developing synthetic Extracellular Matrix (ECM) analogs.

Recently, the VitroGel™ hydrogels have been designed for researchers willing to fully master the characteristics of the synthetic ECM to be used with their 3D / 2D cell cultures. In this post, we will review the main benefits of the recently released VitroGel™ solutions.

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Cell Sourcing - Cell Culture Technologies, Supplying Discovery Tools

3D cell culture validation – impact of physioxic conditions on TIMP-1 expression

24/07/2018 by Isabelle Nobiron, PhD No Comments

When compared to 2D conventional cell culture systems, experimental data obtained with 3D cell culture models have been shown in many instances to be more biologically relevant, closer to clinical conditions (eg. predictive assays/preclinical therapeutic testing).

In this context, tebu-bio laboratories have developed a spheroid platform with a selection of downstream analysis applications such as live cell imaging, microfluidic and physioxia culture conditions or downstream multiplex biomarker quantification, among others.

If you need more physiologically relevant models for your study, but you don’t have access to the technologies or haven’t the time to spend on setting up spheroid cultures in your own laboratories, read on to see what tebu-bio laboratories can generate for you in terms of data.

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News

AIM Biochips – 3D cell culture platform for Immunotherapy and T Cell therapy studies

18/05/2018 by Frédéric Samazan No Comments

As mentioned in a previous post the DAX Biochips from AIM Biotech are an innovative and versatile microfluidic platform, allowing researchers to more easily develop 3D cell culture models, to work as close as possible to what occurs in the human body, but under in-vitro conditions.

Due to its innovative structure (as seen in this general AIM Chips flyer), a broad range of applications have already been validated on this model (Cellular Migration-Invasion Analysis / Angiogenesis studies / Metstasis Modeling System), but what’s new is that now Immunotherapy and T-Cell Therapy studies can be performed on this technology.

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Cell Sourcing - Cell Culture Technologies

AACR2018 – tebu-bio presents “Time-lapse analysis of drug response and invasive capacity…”

26/04/2018 by Sara Pierre No Comments
"Time-lapse analysis of drug response and invasive capacity using patient-derived and CRC microfluidic 3D cancer models under oxygen controlled conditions"

This year again, we were pleased to attend the Annual meeting of the AACR (American Association for Cancer Research), which took place in Chicago, USA earlier this month.

Dora Sabino PhD of tebu-bio at the AACR2018 Poster Session
Dora Sabino PhD of tebu-bio at the AACR2018 Poster Session
Dora Sabino PhD of tebu-bio at the AACR2018 Poster Session
Dora Sabino PhD of tebu-bio at the AACR2018 Poster Session
Dora Sabino PhD of tebu-bio at the AACR2018 Poster Session
Dora Sabino PhD of tebu-bio at the AACR2018 Poster Session

Dora Sabino Ph.D. (3D Cell Culture Project Manager, tebu-bio) presented a poster covering a physiologically relevant study on 3D colon cancer models in microfluidic chips:

“Time-lapse analysis of drug response and invasive capacity using patient-derived and CRC microfluidic 3D cancer models under oxygen controlled conditions”

Download your copy of the poster here and learn more about tebu-bio’s laboratory outsourcing solutions.

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