• Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
  • Facebook
  • LinkedIn
  • Twitter
  • Vimeo
Home
Research areas
    ADME-Tox
    Biomarkers
    Cell Biology and Signalling
    Cell Sourcing - Cell Culture Technologies
    Drug Discovery
    Gene Expression - Molecular Biology
    Stem Cells
    Supplying Discovery Tools
Contact us
Meet the authors
Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Supplying Discovery Tools

New Flipper-TR probes – easily measure membrane tension in cells

25/03/2021 by Frédéric Samazan No Comments

Despite its importance in the regulation of many cellular processes, membrane tension is still complicated to measure. And despite valuable insights, the techniques currently available remain complex and present technical limitations. To overcome these drawbacks, Spirochrome have developed Flipper-TR, the first probes for fluorescence microscopy in the field of mechanobiology, that specifically targets the plasma membrane of cells and reports membrane tension through changes in its fluorescence lifetime.

Continue reading
Supplying Discovery Tools

Siglecs as the new immunecheckpoint target

09/02/2021 by Frédéric Samazan No Comments

Due to their involvement as checkpoints in immune cell responses, Sialic-acid-binding ImmunoGlobulin-like Lectins (Siglecs) have gained more and more interest as therapeutic targets in Immuno-Oncology and Immune regulation. You’ll be interested to learn that BPS Bioscience have developed and released a number of Siglec proteins and stable cell lines, which you can obtain in Europe through tebu-bio.

Continue reading
Supplying Discovery Tools

How can you get your mRNA ready in only a few weeks?

30/11/2020 by Dimitri Szymczak, PhD No Comments

Synthetic mRNA is indeed the highway for today’s therapeutics, whether you’re working on developing new drugs against cancer targets, or whether you aim to develop new vaccines, Covid-19 being one of them. So, how can you obtain your mRNA within just a few weeks, ready to explore these potential applications? Read on to see how we can help you achieve this.

Continue reading
Stem Cells

Consistent, scalable human iPSC-derived glutamatergic neurons and skeletal myocytes

26/11/2020 by Agnès Audrain No Comments

As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™1 (optimized inducible overexpression), that can generate functional cells with high consistency from human induced pluripotent stem cells (iPSCs). opti-ox overcomes gene silencing and enables controlled expression of transcription factors, and as a result, deterministic induction of a new cell identity. The resulting mature cells are physiologically relevant and phenotypically characterised, and for the first time, available at scale, offering predictive, in vitro, cells for research and drug screening.

Here we’ll be taking a closer look at the products already available for researchers. As the technology can be applied to generate many other mature cell types, more will be coming soon, including CNS cells, immune cells, and cells for toxicology and disease modelling.

The first human iPSC-derived products developed using opti-ox are the ioGlutamatergic Neurons and ioSkeletal Myocytes, which are both available across Europe through tebu-bio. There will be more to follow…

Continue reading
Page 5 of 213« First...«4567»102030...Last »

Most popular posts

  • HeLa cells: Origin of this important cell line in life science research
  • How to choose the perfect buffer to get a pure, stabilised, functional protein
  • From RUO to IVD - the acronym guide to reagents' intended use
My Tweets

Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use.
To find out more, including how to control cookies, see here: Cookie Policy

Copyright © 2018 - tebu-bio - visit our main website at tebu-bio.com