BPS Bioscience’s full range of products are available through tebu-bio in Europe.

As a regulator of the immune system, Immune checkpoints appear to be privileged targets In Drug Discovery and Immunotherapy research.  Indeed, promising molecules tested in clinical trials and approved are giving new hope for cancer treatment. Beyond checkpoint receptors, the Enzymatic pathway also regulates the immune system and provides additional targets for Drug Development, and may increase the chances of clinical success in Cancer treatment.

In addition to already developed Immune Checkpoint Reporter cell lines (as introduced in my previous post), BPS Bioscience also provide tools to study the enzymatic pathway, such as the tryptophan catabolism pathway controlled by IDO1: The IDO / TDO pathway.

RayBiotech 2017 Outstanding Distributor Award – tebu-bio Best in Europe.

At the recent meeting of all RayBiotech distributors, Isabelle Nobiron PhD (Product Specialist, tebu-bio), was proud to receive the 2017 Outstanding Distributor Award – Best in Europe.

During this meeting, which took place in Guangzhou (China), RayBiotech (Norcross, USA) also appointed tebu-bio as one of the 3 centers in the world to perform contract research for their high density arrays. Up to 1000 human proteins, 200 mouse and 67 rat biomarkers can be tested on semi-quantitative or quantitative proteomics microarray platforms.

tebu-bio has been a longstanding, recognised RayBiotech Certified Services provider, performing outsourced immunoassays at their European Headquarters situated near Paris (full range of services tebu-bio services here).

RayBiotech, Inc. develop cutting edge proteomics tools for the advancement of basic and clinical research, and the facilitation of drug and biomarker discovery.  Their product-line covers 2,000+ rigorously tested ELISA tests (covered by a 90-day 100% satisfaction guarantee), Multiplex ELISA Arrays (Quantibody®), Membrane- or glass-slide Antibody Arrays (C-Series, G-Series, L-Series, E-Series), Functional assays, Research antibodies and Recombinant proteins.

tebu-bio provides their broad range of products to researchers across Europe. For more details, contact your local tebu-bio office.

Having access to highly reproducible and fully validated ELISA tests is crucial in today’s Life Science research. Although the Sandwich ELISA format is the most commonly used, other immunoassay formats are also available to allow for a complete tool box, from phosphorylation studies to transcription factor activity assays.

In this post, I’ll be taking a look at the 6 formats available.

As discussed previously in our recent Drug Discovery post, Immunotherapy is one of the central research fields for various disease treatments and also certain cancers. A major regulator of immune homoeostasis and preventing autoimmunity, but potentially dysregulated in various cancers, Immune Checkpoint targeting has already led to promising treatment molecules (Nivolumab, Pembrolizumab…).

To face the challenges of Immune system complexity and the tumor microenvironment, BPS Biosciences have developed several reporter cellular lines (the full listing is here) to complement Biochemical assays. By providing more physiological outcomes in a cellular context (functionality of the whole cell signaling pathway) BPS cell lines allow, for example, the identification of an agonist vs antagonistic effect of your candidate.