The 1^st generation of cell therapies uses DNA-based vectors including plasmids and lentivirus, and has demonstrated its efficiency. However, it also raises some questions regarding biosafety, cost, and compatibility with high throughput production. Now, the messenger RNA approach can avoid the genome integration, is safer and can ensure low immune response. So, why not use mRNA for cell therapies?

Many researchers are facing the challenges of mRNA delivery, through the body into the cytoplasm of cells. In this post, we invite you to discover some useful and efficient solutions to improve and control all the steps of your mRNA delivery project.

Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread to become the major health issue of the past two years. But it’s also a research field of interest for many researchers. With the latest findings, SARS-CoV-2 has more to reveal… including one related to ADCC.

Oxidative stress can lead to diverse pathophysiological changes in the body. Neurodegenerative diseases such as Parkinson and Alzheimer are linked to oxidative stress, as well as several cancers and diseases such as chronic fatigue syndrome, fragile X syndrome, heart and blood vessel disorders, heart attack, heart failure, and atherosclerosis (for an overview see Fig. 1). In this post, let’s look at some convenient kits to measure the anti-oxidative potential of your samples!