With the great success of the SIR-probes for efficient labeling of the cell Cytoskeleton, DNA and Lysosome, Spirochrome have just launched a series of 10 new live cell fluorescent tools : The SPY^TM probes.

Developed by Epicypher and available in Europe through tebu-bio, CUTANA CUT&RUN and its sister technology CUT&TAG are quickly becoming the preferred approaches for Chromatin Mapping experiments over the classical method ChiP-Seq. To supplement these advances, EpiCypher is also leading the way for the validation of highly specific antibodies to histone PTMs for chromatin profiling assays. Let’s check how these new antibodies are validated.

Despite its importance in the regulation of many cellular processes, membrane tension is still complicated to measure. And despite valuable insights, the techniques currently available remain complex and present technical limitations. To overcome these drawbacks, Spirochrome have developed the first probe for fluorescence microscopy in the field of mechanobiology, that specifically targets the plasma membrane of cells and reports membrane tension through changes in its fluorescence lifetime : the Flipper-TR^® probe.

Due to their involvement as checkpoints in immune cell responses, the Sialic-acid-binding immunoglobulin-like lectins or Siglecs have gain more and more interest as a therapeutic targets in Immune-Oncology and Immune regulation. To support researchers in their research BPS Bioscience have developed and released a number of Siglec proteins and stable cell lines, available in Europe through tebu-bio.