• Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
  • Facebook
  • LinkedIn
  • Twitter
  • YouTube
Home
Research areas
    ADME-Tox
    Biomarkers
    Cell Biology and Signalling
    Cell Sourcing - Cell Culture Technologies
    Drug Discovery
    Gene Expression - Molecular Biology
    Stem Cells
    Supplying Discovery Tools
Contact us
Meet the authors
tebu-bio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Drug Discovery, Gene Expression - Molecular Biology

5 new research tools to perform chromatin and epigenetic analysis

10/07/2014 by Philippe Fixe, PhD No Comments
Nucleosome schematic structure

Nucleosomes are core particles involved in DNA packaging in eukaryotic cells. They affect gene expression levels  by regulating access of DNA to transcription factors and DNA binding proteins. Nucleosome modeling is not static and chaotic. The link between nucleosome dynamics and gene expression modulation still remains a mystery, driving Life Scientists to design clever nucleosome-based in vitro assays such as those we’ll be reviewing here.

Continue reading
Gene Expression - Molecular Biology

Dual secreted Alkaline Phosphatase and Luciferase detection in one sample

05/06/2014 by Philippe Fixe, PhD No Comments
GLuc and SEAP dual detection assay graph GeneCopoeia tebu-bio

Secrete-Pair™ dual luminescence assay kit analyzes the activities of Gaussia Luciferase (GLuc) and Secreted Alkaline Phosphatase (SEAP) as a dual-reporter system. This dual luminescence assay system includes all reagents needed for an optimal dual luminicent detection of GLuc and SEAP while allowing transfection normalization and side-by-side analysis using the same sample from the cell culture medium.

Continue reading
Gene Expression - Molecular Biology

"CRISPR-Cas9 Specificity: Taming Off-target Mutagenesis" Technical bulletin

22/05/2014 by Philippe Fixe, PhD No Comments
CRISPR/Cas 9 Genome editing and Engineering

The CRISPR (Clustered, Regularly Interspaced, Short Palindromic Repeats)-Cas (CRISPR-associated) (CRISPR-Cas) system has become trendy as it is suitable for numerous applications such as gene knockouts, genome-engineering, to name but a few. In a recent Technical Bulletin, Ed Davis describes the mechanism of CRISPR-Cas for genome editing and how the recent experimental improvements improve CRISPR-Cas9 specificity while reducing off-target effects.

Continue reading
Gene Expression - Molecular Biology, Supplying Discovery Tools

What's Trending in the Molecular Biology World? CRISPR !!!

24/04/2014 by Mark Livingstone 1 Comment
Google Trends shows CRISPR "interest over time" reaching Breakout status

It’s official, CRISPR has officially reached “Breakout” status as a Google search term (see image from Google Trends). The Clustered, Regularly Interspaced, Short Palindromic Repeats (CRISPR) and RNA-guided Cas9 nucleases are an exciting new gene editing tool that allows life science researchers to directly modify the DNA of the organism they study.

Continue reading
Page 19 of 20« First...10«17181920»
tebu-bio

LAB SERVICES OUTSOURCING

• Protein production

• Plasmid Preps

• 3D Cell Culture
LEARN MORE

Top contributors

Dimitri Szymczak, PhD
Dimitri Szymczak, PhD
  • Adenovirus-based KO
  • New – you know CRISPR, now it’s Prime Editing
Frédéric Samazan
Frédéric Samazan
  • Five new fluorescent probes to easily image live cellular processes
  • Immuno-Oncology: 6 must-haves to boost your projects
Isabelle Nobiron, PhD
Isabelle Nobiron, PhD
  • Accelerate your Biomarker discovery with High Density arrays
  • Want to know more about your Biologics?
Isabelle Topin, PhD
Isabelle Topin, PhD
  • Antibody Purification: Tips and Tricks
  • Monoclonal antibodies – all you need to know about antibody generation
Philippe Fixe, PhD
Philippe Fixe, PhD
  • ChIP for sensitive & fast genomic mapping
  • Recent developments in 3D cell culture hydrogel

Copyright © 2018 - tebu-bio - visit our main website at tebu-bio.com