The potential of nanomedicine to provide therapeutic benefits over conventional drug formulations has been proven with a number of drugs on the market. Following the success of DOXIL®, a liposome-based doxorubicin formulation which improves pharmakocinetic profile, DIVERSA have developed a new lipidic nanoemulsion. In this post, we look at how it overcomes the barriers of solubility, permeability and intracellular delivery of small molecules, to help biomedical researchers to reach the preclinical stages. Available in Europe through Tebubio, see how DIVERSA’s new technology can redefine the medicinal chemistry/lead screening workflow.

Even if RNA-based therapeutics have been under development for over 30 years, it was the COVID-19 pandemic that brought them into the limelight, with the rapid development of mRNA-based vaccines against the SARS-Cov2 virus by Moderna and BioNTech/Pfizer. And lipid Nanoparticles (LNPs), used to efficiently deliver mRNA, are key players of this technology.

With the great success of the SIR-probes for efficient labeling of the cell Cytoskeleton, DNA and Lysosome, Spirochrome have just launched a series of 10 new live cell fluorescent tools : The SPY^TM probes.

Developed by Epicypher and available in Europe through tebu-bio, CUTANA CUT&RUN and its sister technology CUT&TAG are quickly becoming the preferred approaches for Chromatin Mapping experiments over the classical method ChiP-Seq. To supplement these advances, EpiCypher is also leading the way for the validation of highly specific antibodies to histone PTMs for chromatin profiling assays. Let’s see how these new antibodies are validated.