AKT (Protein Kinase B or PKB), is a serine/threonine-specific protein kinase with known key involvement in glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.
AKT (Protein Kinase B or PKB), is a serine/threonine-specific protein kinase with known key involvement in glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.
The Notch signaling pathway plays a vital role in the regulation of asymmetric cell division, cell fate specification and proliferation. Mammals possess 4 different Notch receptors, referred to as Notch1, 2, 3, and 4. The Notch receptor is a hetero-oligomer transmembrane protein that comprises a large extracellular domain, a single-pass transmembrane span, and a small intracellular region.