The potential of proteins for the treatment of diseases

Protein therapeutics represents a powerful field for the treatment of many diseases, having shown its potential for several years; especially since the ‘boom’ of recombinant protein production. In this post, we invite you to see the benefits of a new nanotechnology.

When compared to the traditional small molecule therapeutic approach, proteins bring both high biocompatibility and biodegradability. These facts are associated with a high safety profile. When considering activity, proteins present a much more targeted activity, directly related to their specific interaction with the target of interest. However, these molecules can suffer from unfolding and short half-life, due to enzymatic degradation, all associated with loss of activity. Their poor membrane permeability impedes intracellular delivery. All these drawbacks can be overcome using delivery vehicles that can carry, protect, and deliver the cargo.