Due to their involvement as checkpoints in immune cell responses, Sialic-acid-binding ImmunoGlobulin-like Lectins (Siglecs) have gained more and more interest as therapeutic targets in Immuno-Oncology and Immune regulation. You’ll be interested to learn that BPS Bioscience have developed and released a number of Siglec proteins and stable cell lines, which you can obtain in Europe through tebu-bio.