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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
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    • ADME-Tox
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Supplying Discovery Tools

Cell signalling – Discover G-LISA to study Small GTPases

21/06/2018 by Frédéric Samazan No Comments

As is already known, multiple families of small GTPases (Ras, Arf and Rho families) make up the Ras cell signalling - GTPase molecular cycleGTPase superfamily. Due to their role as molecular switches in cell signalling (active GTP-bound state vs inactive GDP-bound states) and in many other cellular responses (cytoskeletal reorganization, regulation of transcription, apoptosis…), these small GTPases are the subject of intense investigation to try to understand the mechanisms that regulate activation and inactivation of this proteins.

In this post, I invite you to discover a revolutionary way to study these cell signalling events by quantifying the level of active small GTPases in your experimental model.

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