New: Nipah Virus G Protein and antibodies for developing specific NiV ELISA test

cell virus, virology

Nipah Virus Infection (NiV) is an emerging infectious disease of public health importance in the South-East Asia Region (source: World Health Organization). Along with Hendra virus (HeV), NiV is part of a new genus designated Henipavirus. Fruit bats have been identified as the natural reservoirs. Nevertheless, pigs, horses, goats, sheep, cats and dogs can also be infected and transmit the virus.

Symptoms of NiV infection are similar to influenza and in some cases can lead to encephalitis. The case fatality rate is high (40-70%) and there is no specific treatment. While able to bind with cellular EphrinB2, NiV G Protein (NiV-G) exhibits the antigenic epitopes and conformation necessary for specific antigen–antibody recognition. For this reason, Meridian Life Science have recently developed new Nipah virus glycoprotein (NiV-G) products suitable for the R&D projects of NiV using ELISA tests.

New Nipah Virus G Proteins & monoclonal antibodies (MAbies)

Ephrin B2 (EPHB2) detection by IF in HeLa (up) and HepG2 (bottom) cells with anti-EPHB2 monoclonal antibody cat. nr MAB10592 clone 2D12C6 – abnova tebu-bio

All these novelties are compatible with ELISA test applications.

These MAbies can be used as a pair in sandwich ELISA with the recombinant protein or in capture IgM assays.

These new items are available from tebu-bio from research use only (RUO) and ideal companion for NiV-related biomarker analysis.

1- C01974M-0.5 – MAb to Nipah Virus G Protein

  • Reacts with rec. Nipah Virus G protein
  • Does not cross react with Dengue, Zika and Chikungunya env. protein
  • Produced in Cell Culture
  • Compatible with ELISA test (detection Aby)
  • C01974M CoA

2- C01975M-0.5 MAb to Nipah Virus G Protein

  • Reacts with rec. Nipah Virus G protein
  • Does not cross react with Dengue, Zika and Chikungunya env. protein
  • Produced in Cell Culture
  • Compatible with ELISA test (capture Aby)
  • C01975M CoA

3- R01766-0.1 Nipah Virus G Protein, Rec.

  • Amino acid sequence is highly conserved among human, pig and bat
  • Suitable for use as a control
  • Produced in Insect Cells
  • Compatible with ELISA test (as the recombinant Antigen)
  • R01766 CoA

Looking for more viral related antibodies or antigens for your research projects?

Contact your local tebu-bio office here.

Philippe Fixe, PhD
Written by Philippe Fixe, PhD
Philippe Fixe is Marketing Director at tebu-bio, passionate about innovation and R&D in Life sciences, Biotechnology, Medical research, Drug discovery, and also a keen photographer.