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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
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    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
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Cell Biology and Signalling

New TIGIT:CD155 cell-based assay to restore immune response

23/05/2017 by Dimitri Szymczak, PhD No Comments
immune inhibition and activation

TIGIT:CD155/CD112 immune inhibition (in green)

We previously addressed the PD-1:PD-L1/PD-L2 immune inhibition and the corresponding cell-based tools to screen immuno-oncology agents for restoring antitumor immune response. Unfortunately cancer cells have other ways to escape and survive. Let’s look together at another immune inhibition pathway, namely the TIGIT:CD155/CD112.

 

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