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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
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    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
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Drug Discovery

New research tools targeting PCSK9 and LDLR

01/09/2016 by Ali El Baya, PhD No Comments
anti PCSK9 neutralizing ab - results

There is an increasing demand for new cholesterol-lowering therapies in addition to existing treatments (e.g. targeting statins). The pharmacological inhibition of PCSK9-mediated LDLR degradation is becoming very attractive for treating cholesterol-related diseases. But which reliable in vitro assays are available to effectively study “PCSK9-LDLR” interactions ?

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