• Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
  • Facebook
  • LinkedIn
  • Twitter
  • Vimeo
Home
Research areas
    ADME-Tox
    Biomarkers
    Cell Biology and Signalling
    Cell Sourcing - Cell Culture Technologies
    Drug Discovery
    Gene Expression - Molecular Biology
    Stem Cells
    Supplying Discovery Tools
Contact us
Meet the authors
Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
News

1,4-DPCA triggers tissue renewal in mouse ears

26/08/2015 by Philippe Fixe, PhD No Comments
Bioactive small molecules from tebu-bio

The Murphy Roths Large-MRL engineered mouse strain spontaneously regenerates ears and even heart tissue.  Such a regenerative process is known for amphibians; mammals generally forming scar tissue during the process of wound repair. The groups of Ellen Heber-Katz (The Wistar Institute, Philadelphia, PA) and Phillip B. Messersmith (Northwestern University, Evanston, IL) discovered these exceptional capabilities a few years ago. By using this unique model, the scientists have recently shown that Hypoxia-Inducible Factor-1 alpha (HIF-1alpha) is involved in mammalian tissue regeneration (Zhang Y. et al. “Drug-induced regeneration in adult mice”(2015) Sci. Transl. Med. DOI: 10.1126/scitranslmed.3010228).

Continue reading

Most popular posts

  • HeLa cells: Origin of this important cell line in life science research
  • How to choose the perfect buffer to get a pure, stabilised, functional protein
  • From RUO to IVD - the acronym guide to reagents' intended use
My Tweets

Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use.
To find out more, including how to control cookies, see here: Cookie Policy

Copyright © 2018 - tebu-bio - visit our main website at tebu-bio.com