Nowadays in Cancer research, there is a strong need for three-dimensional (3D) in vitro experimental approaches that mimick as much as possible the in vivo tumour ecosystem. In addition to solving issues related to animal models, these in vitro 3D models allow precise tuning of experimental design when investigating cancer cell biology but also, compound screening and disease modelling. In this post, we’ll take a look at the growth of the popular breast cancer cell line, MCF-7, using Alvetex^®Scaffold technology (Reinnervate – a ReproCell company) to create a 3D structure that closely resembles the structure of tumour tissues grown in vivo.

tebu-bio is pleased to announce their sponsorship of the 1st Course on “Post-transcriptional gene regulation: mechanisms at the heart of networks” (Institut Curie, March 23-27, 2015) that will be training 40 PhD students and postdoctoral fellows from 10 countries. Post-transcriptional gene regulation refers to every level of gene-expression control in a cell that occurs between transcription and the resulting protein levels. Specialists in this field study such things as polyadenylation, miRNAs, RNA binding proteins, signal transduction, and (pre)mRNA splicing.