Kv1.3 channels are expressed in T-cell lymphocytes and over-expressed in autoimmune diseases. They can be see as a therapeutic taget for T cell mediated autoimmune diseases.

For years, clinicians and researchers have gathered enormous collections of samples coming from different patients. These samples enable retrospective studies in order to better understand the mechanisms underlying a variety of diseases, helping to find novel biomarkers for early diagnosis, prognosis or evaluate the response to treatment.