Zebrafish – an ideal model for morphogenesis analysis
In a recent study, Xiong F. et al. have developed a robust Zebrafish-based model allowing the analysis of the impact of cell shape and division orientation on epithelial development. This model explores possible links between cell shape and division orientation in epithelial diversity.
Among all the research tools used, the team of scientists investigated Cdh1 expression by IHC-Wm with a Genetex antibody, dedicated to Zebrafish studies (cat. nr GTX125890). This unique antibody is available in Europe thorugh tebu-bio for IHC applications (recommended dilutions 1:100-1:1000) including IHC Whole mount (IHC-Wm).
This emphasizes the need for researchers to have access to high quality and validated antibodies focused on Zebrafish model, as described in a previous post, showing the benefits of using such primary antibodies in Zebrafish whole mount IHC staining.
Xiong F. et al. “Interplay of Cell Shape and Division Orientation Promotes Robust Morphogenesis of Developing Epithelia” Cell Volume 159, Issue 2, p415–427. DOI: http://dx.doi.org/10.1016/j.cell.2014.09.007