Zebrafish – an ideal model for morphogenesis analysis

There's a zebra antibody for that! - Genetex |tebu-bio
Cdh1 antibody - Rabbit Polyclonal antibody to E-cadherin (Gentex | tebu-bio)

E-Cadherin (Cdh1) expression in Zebrafish with Genetex antibody (GTX125890 | tebu-bio)

In a recent study, Xiong F. et al. have developed a robust Zebrafish-based model allowing the analysis of the impact of cell shape and division orientation on epithelial development. This model explores possible links between cell shape and division orientation in epithelial diversity.

Among all the research tools used, the team of scientists investigated Cdh1 expression by IHC-Wm with a Genetex antibody, dedicated to Zebrafish studies (cat. nr GTX125890). This unique antibody is available in Europe thorugh tebu-bio for IHC applications (recommended dilutions 1:100-1:1000) including IHC Whole mount (IHC-Wm).

This emphasizes the need for researchers to have access to high quality and validated antibodies focused on Zebrafish model, as described in a previous post, showing the benefits of using such primary antibodies in Zebrafish whole mount IHC staining.
Xiong F. et al. “Interplay of Cell Shape and Division Orientation Promotes Robust Morphogenesis of Developing Epithelia” Cell Volume 159, Issue 2, p415–427. DOI: http://dx.doi.org/10.1016/j.cell.2014.09.007

Philippe Fixe, PhD
Written by Philippe Fixe, PhD
Philippe Fixe is Marketing Director at tebu-bio, passionate about innovation and R&D in Life sciences, Biotechnology, Medical research, Drug discovery, and also a keen photographer.