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    ADME-Tox
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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
News

Researcher's Travel Grant: a new photo from one of our April winners!

27/06/2014 by Elodie Monin No Comments

Image1 We’d like to share a photo sent by one of our Travel Grants Winners in April! She is in the middle, first line with a turquoise jacket.

 

Anita is just back from the EBI-EMBL Networks and Pathways course . Her tebu-bio Travel Grant helped her to participate in this course.

 

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Supplying Discovery Tools

Focus on the Hypoxia Pathway…

by Elodie Monin No Comments
hypoxia pathway

Hypoxia in tumors is closely associated with tumor aggressiveness and resistance to radio- and chemotherapeutic treatment. Therefore, reliable markers for hypoxia represent both valuable diagnostic markers and potential targets for investigation.

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ADME-Tox, Cell Sourcing - Cell Culture Technologies, Drug Discovery

Plateable Hepatocytes… the "one cell type doesn't fit all" syndrome

by Jean-François Têtu, PhD No Comments

Hepatocytes are commonly used in drug discovery and preclinical drug development to perform experiments requiring intact cellular systems. Intact hepatocytes contain the major hepatic drug-metabolizing enzymes required to study the four categories of xenobiotic biotransformation: Hydrolysis, Reduction, Oxidation and Conjugation. Because of these enzymes, hepatocytes provide a viable and cost-effective alternative to in vivo compound testings.

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