• Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
  • Facebook
  • LinkedIn
  • Twitter
  • Vimeo
Home
Research areas
    ADME-Tox
    Biomarkers
    Cell Biology and Signalling
    Cell Sourcing - Cell Culture Technologies
    Drug Discovery
    Gene Expression - Molecular Biology
    Stem Cells
    Supplying Discovery Tools
Contact us
Meet the authors
Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
    • Cell Biology and Signalling
    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
    • Supplying Discovery Tools
  • Contact us
  • Meet the authors
Cell Sourcing - Cell Culture Technologies

Unlimited sources of neural cells mimicking CNS disorders for in vitro bioassays

21/05/2014 by Philippe Fixe, PhD No Comments
XCell Sciences - tebu-bio Human Stem Cell & CNS Research

Access to neural cellular models for in vitro Neuroscience research enters into a new era.

XCell Science, experts in cellular and genome engineering, provide genetically modified cellular models differentiated from Human induced Pluripotent Stem Cell (iPSC) lines. tebu-bio bring its scientific and logistics skills to deliver in Europe these high-quality and characterized neural cell derivatives for R&D, drug discovery, toxicology and regenerative medicine approaches.

Unlimited sources of biologically relevant functional neural cells

Proprietary high-efficiency protocols allow the directed differentiation of these iPS lines into a variety of functional neural cells, such as:A large collection of neural cells (XCell Science - tebu-bio)

  • Neural Stem Cells (NSC),
  • Neurons,
  • Dopaminergic neurons,
  • Astrocytes.

Disease-specific knock-out isogenic neural cell lines

tebu-bio’s experts are pleased to introduce a collection of isogenic knock-out iPSC lines mimicking genetic defects identified in CNS disorders (Parkinson’s and Alzheimer’s diseases, Autism, Schizophrenia and Amyotrophic Lateral Sclerosis (ALS)):

  • BDNF-/-: Homozygous knockout of the BDNF gene,

    Dopa Neural Cells (XCell Science by tebu-bio)

    Expression of TH in Ready-to-use XCell DOPA cells prolonged cultured in DOPA medium.

  • APOE-/-: Homozygous knockout of the APOE gene,
  • DISC1-/-: Homozygous knockout of the DISC1 gene,
  • CNTNAP2-/-: Homozygous knockout of the CNTNAP2 gene,
  • SOD1-/-: Homozygous knockout of the SOD1 gene,
  • Park2-/-: Homozygous knockout of the Park2 gene,
  • Park7-/-: Homozygous knockout of the Park7 gene.

Want to know more about these unlimited iPSC-derived neural cellular models ?

XCell Science logo by tebu-bio

XCell Science by tebu-bio

 

Be among the first to receive the XCell Science launch pack by tebu-bio to optimise your in vitro CNS-specific cellular models.

Sign up now!

 

iPSC-derived Neural cells characterization - XCell Science by tebu-bio

iPSC-derived Neural cells characterization – XCell Science by tebu-bio

Related posts regarding CNS and Stem cell studies:

  • 3 unique Amyloid Beta peptide (Aß) research tools to boost Alzheimer’s Disease research
  • 5 reasons to prefer the MOAB-2 antibody in Alzheimer‘s Disease research
  • How is Amylo-Glo a brighter, longer lasting and higher definition Amyloid plaque marker?
  • Return of SIRT1 deacetylase – Why is SIRT1 so attractive in Drug discovery and Stem cell research?
  • 3 fluorogenic substrates for analyzing undifferentiated iPS and Stem cells
  • Study how miRNAs regulate Stem cell homeostasis and differentiation

 

Most popular posts

  • HeLa cells: Origin of this important cell line in life science research
  • Monoclonal antibodies - all you need to know about antibody generation
  • How to choose the perfect buffer to get a pure, stabilised, functional protein
My Tweets

Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use.
To find out more, including how to control cookies, see here: Cookie Policy

Copyright © 2018 - tebu-bio - visit our main website at tebu-bio.com

 

Loading Comments...