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Tebubio's blog - Acting and reacting in life sciences and biotechnologies
  • Home
  • Research areas
    • ADME-Tox
    • Biomarkers
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    • Cell Sourcing – Cell Culture Technologies
    • Drug Discovery
    • Gene Expression – Molecular Biology
    • Stem Cells
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News

German Society for Cell Biology Meeting | March 18 – 21, 2014

12/03/2014 by Philippe Fixe, PhD No Comments

The International Meeting of the German Society for Cell Biology (DGZ) will take place on March 18 – 21, 2014 (Regensburg).

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News

A new publication by BenMohamed F. et al. investigating the role of TLR9 in pulmonary infections

by Philippe Fixe, PhD No Comments
Research and Development, research applications

The authors have investigated the role Toll-Like Receptor 9 (TLR9) in host defense during Pseudomonas aeruginosa lung infection.

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Biomarkers, Cell Biology and Signalling

2 cost-effective antibody options for Hypoxia pathway analysis

by Philippe Fixe, PhD No Comments
HIF1 alpha GTX127309 (IFA)

Low oxygen tension, or Hypoxia, regulates numerous cellular and tissular functions. In cancer research, hypoxia is a key regulator of tumor development, aggressiveness and therapy resistance by acting on malignant cells and their microenvironment. Hypoxia is also involved in age-related diseases and acts through intracellular and intercellular cascade of events (exosomes, paracrine loops, angiogenesis…) (1-2).

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Drug Discovery

Histone Peptide Arrays' contribution in Epigenetic studies

by Philippe Fixe, PhD No Comments
EpiGold™ Histone Peptide Array Data-ECL

EpiGold™ Histone Peptide Array Data-FluorescenceDNA methylation and histone post-translational modifications are key epigenetic factors.

They regulate gene expression by interfering with the chromatin structure and the binding of effector proteins to post-translational modified histones (1).

Several experimental strategies to analyze such binding have recently been designed; histone modified peptide arrays being one of them.

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