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100ul EUR 539
539€


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Anti CD95/FAS (C-terminus)

Product name
Anti CD95/FAS (C-terminus)
Catalog number
MB0079-100ul (100ul)
Description
Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immuno- surveillance against virus-infected or transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FASbased mechanism involves the transducing molecule FAS (also designated APO-1) and its ligand (FAS-L). The human FAS protein is a cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, certain of which undergo apoptosis in response to treatment with antibody to FAS. These findings strongly imply that targeted cell death is potentially mediated by the intercellular interactions of FAS with its ligand or effectors, and that FAS may be critically involved in CTL-mediated cytotoxicity.-Purified mouse monoclonal in buffer containin 
Source
Bioworld technology
Product category
Antibodies
Product sub category
Primary Antibodies
Target species
Human
Target's name
Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating, surface antigen FAS, FASLG receptor, CD95, FAS, APT1, FAS1, TNFRSF6
Host
Mouse
Clonality
Monoclonal
Application
WB
Shipment info
Cool Pack
Nacres Codification
NA.41

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