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100mg EUR 127

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Recent History

All-Trans Retinoic Acid

Product name
All-Trans Retinoic Acid
Catalog number
04-0021 (100mg)
Stemolecule All-Trans Retinoic Acid is the oxidized form of Vitamin A and functions as a signaling molecule for various developmental pathways that control differentiation and proliferation1,2. It acts by binding to heterodimers of the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), which then bind to retinoic acid response elements (RAREs) in the regulatory regions activating gene transcription3. All-Trans Retinoic Acid has been implicated in specification of the embryonic anterior/posterior axis through Hox gene regulation4. It has been used in various differentiation protocols, including B-cells, T cells and neurons and applied clinically to treat cancer as a form of differentiation-induction therapy2,5-11. 
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Biological activity
Shipment info
Room Temperature
Nacres Codification

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