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2mg EUR 262
262€
10mg EUR 1149
1149€


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CHIR99021

Product name
CHIR99021
Catalog number
04-0004 (2mg)
04-0004-10 (10mg)
Description
The aminopyrimidine CHIR99021 is the most selective inhibitor of glycogen synthase kinase 3Beta (GSK-3Beta) reported to date. Unlike other potent inhibitors of GSK-3, CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3Beta compared to CDKs. Along with the elimination of differentiation-inducing signaling from mitogen-activated protein kinases, using CHIR99021 to block the activity of GSK-3Beta enables the self-renewal of embryonic stem cells. 
Source
Stemgent
Product category
Molecules
Product sub category
Chemicals
Biological activity
 
Pathway
Stem Cells
Shipment info
Room Temperature
Nacres Codification
NA.28

Protocol

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