SNAP-CUTANA™ K-MetStat Panel

• Specifications
• Datasheet

Product name

SNAP-CUTANA™ K-MetStat Panel

Catalog number

19-1002 (50 Reactions)

Description

The SNAP-CUTANA K-MetStat Panel of spike-in controls for CUT&RUN and CUT&Tag offers an all-in-one solution to determine antibody specificity for histone post-translational modifications (PTMs), monitor assay success, and normalize data for quantitative chromatin mapping. The panel contains designer nucleosomes (dNucs) representing 16 different K-methyl PTM states: mono-, di-, and trimethylation at H3K4, H3K9, H3K27, H3K36, & H4K20, as well as unmodified control. Each PTM is represented by two unique DNA-barcoded templates. Each dNuc is individually conjugated to paramagnetic beads and pooled into a single panel for convenient one-step spike-in to CUT&RUN and CUT&Tag experiments. The panel is added to samples alongside ConA-immobilized cells prior to the addition of an antibody targeting a histone lysine methylation state or IgG negative control. pAG-MNase-mediated release or pAG-Tn5-mediated t 

Source

EpiCypher, Inc.

Product category

Genomics

Product sub category

DNA Sequencing

Shipment info

Cool Pack

Nacres Codification

NA.55