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50ug EUR 220
220€
5x10ug EUR 275
275€
100ug EUR 385
385€


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Mambalgin-1

Product name
Mambalgin-1
Catalog number
MAM001-00050 (50ug)
MAM001-50010 (5x10ug)
MAM001-00100 (100ug)
Description
Mambalgin-1 is a potent and selective blocker of acid-sensing ion channels (ASIC). ASIC channels have been demonstrated to be implied in pain pathways and appear to be promising therapeutic targets. Mambalgin-1 rapidly and reversibly inhibits recombinant homomeric ASIC1a (IC50=55 nM) and heteromeric ASIC1a ASIC2a (IC50=246 nM) or ASIC1a ASIC2b channels (IC50=61 nM) but also human channels hASIC1b (IC50=192 nM) and hASIC1a hASIC1b (IC50=72nM).-Sequence: Leu-Lys-Cys3-Tyr-Gln-His-Gly-Lys-Val-Val-Thr-Cys12-His-Arg-Asp-Met-Lys-Phe-Cys19-Tyr-His-Asn-Thr-Gly-Met-Pro-Phe-Arg-Asn-Leu-Lys-Leu-Ile-Leu-Gln-Gly-Cys37-Ser-Ser-Ser-Cys41-Ser-Glu-Thr-Glu-Asn-Asn-Lys-Cys49-Cys50-Ser-Thr-Asp-Arg-Cys55-Asn-Lys -OH -Disulfide bonds: Cys3-Cys19, Cys12-Cys37, Cys41-Cys49, Cys50-Cys55- 
Source
Smartox Biotechnology
Product category
Proteins & Peptides
Product sub category
Peptides
Label
No
Shipment info
Room Temperature
Nacres Codification
NA.26

Protocol

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