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5x10ug EUR 165
165€
100ug EUR 198
198€
500ug EUR 578
578€
1mg EUR 985
985€


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Alpha-conotoxin GID

Product name
Alpha-conotoxin GID
Catalog number
CON019-50100 (5x10ug)
CON019-00100 (100ug)
CON019-00500 (500ug)
CON019-01000 (1mg)
Description
AA sequence:Ile-Arg-Asp-Gla-Cys5-Cys6-Ser-Asn-Pro-Ala-Cys11-Arg-Val-Asn-Asn-Hyp-His-Val-Cys19-OH-Disulfide bonds: Cys5-Cys11 and Cys6-Cys19-Alpha-conotoxin GID is a peptide originally isolated from the venom of the Conus geographus. It is composed of 19 amino acids and is folded by two disulphide bonds connecting Cys1-Cys3 and Cys2-Cys4. Based on the number of amino acids between the second and the third cysteine residues (loop I) and the third and fourth cysteine residues (loop II), Alpha-conotoxin GID belongs to the Alpha4/7-conotoxin family. Alpha-conotoxin GID blocks selectively neuronal nicotinic acetylcholine receptors with IC50 values of 3 nM (Alpha3Beta2 nicotinic receptors), 5 nM (Alpha7) and 150 nM (Alpha4Beta2). Alpha-conotoxin GID is at least 1000-fold less potent onto the Alpha1Beta1GammaDelta, Alpha3Beta4, and Alpha4Beta4 nicotinic receptors. Alpha-conotoxin GID is a unique Alpha4/7-conotoxin because of its ability to block both Alpha7 and Alpha3Beta2 isoforms, contrary 
Source
Smartox Biotechnology
Product category
Proteins & Peptides
Product sub category
Peptides
Label
No
Shipment info
Room Temperature
Nacres Codification
NA.26

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